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Transient enhanced IL-2R signaling early during priming rapidly amplifies development of functional CD8(+) T effector-memory cells
Much is known concerning the cellular and molecular basis for CD8(+) T memory immune responses. Nevertheless, conditions that selectively support memory generation have remained elusive. Here we show that an immunization regimen that delivers TCR signals through a defined antigenic peptide, inflamma...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3478487/ https://ncbi.nlm.nih.gov/pubmed/23018461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202067 |
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