Llwytho...

Transient enhanced IL-2R signaling early during priming rapidly amplifies development of functional CD8(+) T effector-memory cells

Much is known concerning the cellular and molecular basis for CD8(+) T memory immune responses. Nevertheless, conditions that selectively support memory generation have remained elusive. Here we show that an immunization regimen that delivers TCR signals through a defined antigenic peptide, inflamma...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Castro, Iris, Dee, Michael J., Malek, Thomas R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478487/
https://ncbi.nlm.nih.gov/pubmed/23018461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202067
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