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Sonic hedgehog in the notochord is sufficient for patterning of the intervertebral discs

The intervertebral discs, located between adjacent vertebrae, are required for stability of the spine and distributing mechanical load throughout the vertebral column. All cell types located in thes middle regions of the discs, called nuclei pulposi, are derived from the embryonic notochord. Recentl...

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Autores principales: Choi, Kyung-Suk, Lee, Chanmi, Harfe, Brian D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478436/
https://ncbi.nlm.nih.gov/pubmed/22841806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2012.07.003
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