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Hedgehog signaling is required for formation of the notochord sheath and patterning of nuclei pulposi within the intervertebral discs
The vertebrae notochord is a transient rod-like structure that produces secreted factors that are responsible for patterning surrounding tissues. During later mouse embryogenesis, the notochord gives rise to the middle part of the intervertebral disc, called the nucleus pulposus. Currently, very lit...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3111270/ https://ncbi.nlm.nih.gov/pubmed/21606373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007566108 |
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