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Three novel acetylation sites in the Foxp3 transcription factor regulate the suppressive activity of regulatory T cells
The Foxp3 transcription factor is the master regulator of regulatory T cell (Treg) differentiation and function. Its activity is regulated by reversible acetylation. Using mass spectrometry of immunoprecipitated proteins, we identify three novel acetylation sites in murine Foxp3 (K31, K262, and K267...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3478122/ https://ncbi.nlm.nih.gov/pubmed/22312127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100903 |
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