Llwytho...

Neutralizing antibodies to therapeutic enzymes: considerations for testing, prevention and treatment

Lysosomal storage diseases are characterized by deficiencies in lysosomal enzymes, allowing accumulation of target substrate in cells and eventually causing cell death. Enzyme replacement therapy is the principal treatment for most of these diseases. However, these therapies are often complicated by...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wang, Jinhai, Lozier, Jay, Johnson, Gibbes, Kirshner, Susan, Verthelyi, Daniela, Pariser, Anne, Shores, Elizabeth, Rosenberg, Amy
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478093/
https://ncbi.nlm.nih.gov/pubmed/18688246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1484
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