Persistence of Repair Proteins at Unrepaired DNA Damage Distinguishes Diseases with ERCC2 (XPD) Mutations: Cancer-Prone Xeroderma Pigmentosum vs. Non-Cancer-Prone Trichothiodystrophy

Patients with xeroderma pigmentosum (XP) have a 1,000-fold increase in ultraviolet (UV)-induced skin cancers while trichothiodystrophy (TTD) patients, despite mutations in the same genes, ERCC2 (XPD) or ERCC3 (XPB), are cancer-free. Unlike XP cells, TTD cells have a nearly normal rate of removal of...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Boyle, Jennifer, Ueda, Takahiro, Oh, Kyu-Seon, Imoto, Kyoko, Tamura, Deborah, Jagdeo, Jared, Khan, Sikandar G., Nadem, Carine, DiGiovanna, John J., Kraemer, Kenneth H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477783/
https://ncbi.nlm.nih.gov/pubmed/18470933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.20768
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller