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Theoretical study of L-type Ca(2+) current inactivation kinetics during action potential repolarization and early afterdepolarizations
Sarcoplasmic reticulum (SR) Ca(2+) release mediates excitation–contraction coupling (ECC) in cardiac myocytes. It is triggered upon membrane depolarization by entry of Ca(2+) via L-type Ca(2+) channels (LTCCs), which undergo both voltage- and Ca(2+)-dependent inactivation (VDI and CDI, respectively)...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Blackwell Science Inc
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3477752/ https://ncbi.nlm.nih.gov/pubmed/22586219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.231886 |
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