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Populated Intermediates in the Thermal Unfolding of the Human Telomeric Quadruplex

Thermal denaturation profiles of several model oligonucleotides of the human telomere DNA sequence including d[A(GGGTTA)(3)GGG] (Tel22) were determined using circular dichroism (CD), fluorescence of adenine → 2-aminopurine analogs and fluorescence resonance energy transfer (FRET) to monitor the unfo...

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Bibliographic Details
Main Authors: Gray, Robert D., Buscaglia, Robert, Chaires, Jonathan B.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477705/
https://ncbi.nlm.nih.gov/pubmed/22989179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja307543z
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