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Linkage of cation binding and folding in human telomeric quadruplex DNA
Formation of DNA quadruplexes requires monovalent cation binding. To characterize the cation binding stoichiometry and linkage between binding and folding, we carried out KCl titrations of Tel22 (d[A(GGGTTA)(3)]), a model of the human telomere sequence, using a fluorescent indicator to determine [K(...
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| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2011
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3166971/ https://ncbi.nlm.nih.gov/pubmed/21764207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2011.06.012 |
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