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Evolutionary history of human disease genes reveals phenotypic connections and comorbidity among genetic diseases
The extent to which evolutionary changes have impacted the phenotypic relationships among human diseases remains unclear. In this work, we report that phenotypically similar diseases are connected by the evolutionary constraints on human disease genes. Human disease groups can be classified into slo...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3477654/ https://ncbi.nlm.nih.gov/pubmed/23091697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00757 |
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