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Chapter 2: Mechanistic Aspects of COX-2 Expression in Colorectal Neoplasia
The cyclooxygenase-2 (COX-2) enzyme catalyzes the rate-limiting step of prostaglandin formation in pathogenic states and a large amount of evidence has demonstrated constitutive COX-2 expression to be a contributing factor promoting colorectal cancer (CRC). Various genetic, epigenetic, and inflammat...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3477597/ https://ncbi.nlm.nih.gov/pubmed/22893198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-642-30331-9_2 |
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