Syk Kinase-Coupled C-type Lectin Receptors Engage Protein Kinase C-δ to Elicit Card9 Adaptor-Mediated Innate Immunity

C-type lectin receptors (CLRs) that couple with the kinase Syk are major pattern recognition receptors for the activation of innate immunity and host defense. CLRs recognize fungi and other forms of microbial or sterile danger, and they induce inflammatory responses through the adaptor protein Card9...

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Autori principali: Strasser, Dominikus, Neumann, Konstantin, Bergmann, Hanna, Marakalala, Mohlopheni J., Guler, Reto, Rojowska, Anna, Hopfner, Karl-Peter, Brombacher, Frank, Urlaub, Henning, Baier, Gottfried, Brown, Gordon D., Leitges, Michael, Ruland, Jürgen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477316/
https://ncbi.nlm.nih.gov/pubmed/22265677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.11.015
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