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2C-Methyl-d-erythritol 4-phosphate enhances and sustains cyclodiphosphate synthase IspF activity

There is significant progress toward understanding catalysis throughout the essential MEP pathway to isoprenoids in human pathogens; however, little is known about pathway regulation. The present study begins by testing the hypothesis that isoprenoid biosynthesis is regulated via feedback inhibition...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bitok, J. Kipchirchir, Freel Meyers, Caren
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477264/
https://ncbi.nlm.nih.gov/pubmed/22839733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300243w
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