Inhibition of Hepatitis B Virus and Induction of Hepatoma Cell Apoptosis by ASGPR-Directed Delivery of shRNAs

Hepatitis B virus (HBV) infection is a worldwide liver disease and nearly 25% of chronic HBV infections terminate in hepatocellular carcinoma (HCC). Currently, there is no effective therapy to inhibit HBV replication and to eliminate hepatoma cells, making it highly desired to develop novel therapie...

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Detalhes bibliográficos
Principais autores: Ma, Jingwei, Huang, Chunmei, Yao, Xinxin, Shi, Chuan, Sun, Lifang, Yuan, Lu, Lei, Ping, Zhu, Huifen, Liu, Hongbo, Wu, Xiongwen, Ning, Qin, Zhou, Chun, Shen, Guanxin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477153/
https://ncbi.nlm.nih.gov/pubmed/23094023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046096
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