Co-Operative Additive Effects between HLA Alleles in Control of HIV-1

BACKGROUND: HLA class I genotype is a major determinant of the outcome of HIV infection, and the impact of certain alleles on HIV disease outcome is well studied. Recent studies have demonstrated that certain HLA class I alleles that are in linkage disequilibrium, such as HLA-A*74 and HLA-B*57, appe...

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Autors principals: Matthews, Philippa C., Listgarten, Jennifer, Carlson, Jonathan M., Payne, Rebecca, Huang, Kuan-Hsiang Gary, Frater, John, Goedhals, Dominique, Steyn, Dewald, van Vuuren, Cloete, Paioni, Paolo, Jooste, Pieter, Ogwu, Anthony, Shapiro, Roger, Mncube, Zenele, Ndung'u, Thumbi, Walker, Bruce D., Heckerman, David, Goulder, Philip J. R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477121/
https://ncbi.nlm.nih.gov/pubmed/23094091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047799
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