Ligand-free estrogen receptor activity complements IGF1R to induce the proliferation of the MCF-7 breast cancer cells

BACKGROUND: Ligand-dependent activation of the estrogen receptor (ER) as well as of the insulin-like growth factor type 1 (IGF1R) induces the proliferation of luminal breast cancer cells. These two pathways cooperate and are interdependent. We addressed the question of the mechanisms of crosstalk be...

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Bibliografiske detaljer
Main Authors: Gaben, Anne-Marie, Sabbah, Michèle, Redeuilh, Gérard, Bedin, Monique, Mester, Jan
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476977/
https://ncbi.nlm.nih.gov/pubmed/22799881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-291
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