Loss of WISP2/CCN5 in Estrogen-Dependent MCF7 Human Breast Cancer Cells Promotes a Stem-Like Cell Phenotype

It has been proposed that the epithelial-mesenchymal transition (EMT) in mammary epithelial cells and breast cancer cells generates stem cell features. WISP2 (Wnt-1-induced signaling protein-2) plays an important role in maintenance of the differentiated phenotype of estrogen receptor-positive breas...

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Главные авторы: Ferrand, Nathalie, Gnanapragasam, Anne, Dorothee, Guillaume, Redeuilh, Gérard, Larsen, Annette K., Sabbah, Michèle
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912128/
https://ncbi.nlm.nih.gov/pubmed/24498388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087878
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