Methylation of HIN-1, RASSF1A, RIL and CDH13 in breast cancer is associated with clinical characteristics, but only RASSF1A methylation is associated with outcome

BACKGROUND: Aberrant promoter CpG island hypermethylation is associated with transcriptional silencing. Tumor suppressor genes are the key targets of hypermethylation in breast cancer and therefore may lead to malignancy by deregulation of cell growth and division. Our previous pilot study with pair...

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Bibliografiske detaljer
Main Authors:	Xu, Jia, Shetty, Priya B, Feng, Weiwei, Chenault, Carol, Bast, Robert C, Hilsenbeck, Susan G, Yu, Yinhua
Format:	Artigo
Sprog:	Inglês
Udgivet:	BioMed Central 2012
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3476972/ https://ncbi.nlm.nih.gov/pubmed/22695491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-243
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Methylation of HIN-1, RASSF1A, RIL and CDH13 in breast cancer is associated with clinical characteristics, but only RASSF1A methylation is associated with outcome

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