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Parallel lipoplex folding pathways revealed using magnetic tweezers
Lipid-coated DNA nanoparticles (lipoplexes) are a powerful gene delivery tool with promising therapeutic applications. The mechanism of lipoplex assembly remains poorly understood. We explored DNA packing by a cationic lipid DSTAP (distearoyl trimethylammonium-propane) using magnetic tweezers. DSTAP...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3476939/ https://ncbi.nlm.nih.gov/pubmed/22988939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm301155w |
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