The Effect of Direct Renin Inhibition Alone and in Combination With ACE Inhibition on Endothelial Function, Arterial Stiffness, and Renal Function in Type 1 Diabetes

OBJECTIVE: Diabetes is associated with renin-angiotensin system (RAS) activation, leading to renal and systemic vascular dysfunction that contribute to end-organ injury and significant morbidity. RAS blockade with ACE inhibitors reduces, but does not abolish, RAS effects. Accordingly, our aim was to...

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Detalhes bibliográficos
Main Authors: Cherney, David Z.I., Scholey, James W., Jiang, Shan, Har, Ronnie, Lai, Vesta, Sochett, Etienne B., Reich, Heather N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2012
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476932/
https://ncbi.nlm.nih.gov/pubmed/22837362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc12-0773
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