Effect of Direct Renin Inhibition on Renal Hemodynamic Function, Arterial Stiffness, and Endothelial Function in Humans With Uncomplicated Type 1 Diabetes: A pilot study

OBJECTIVE: Blockade of the renin-angiotensin system (RAS) plays an important role in preventing end-organ injury associated with diabetes. The recent development of direct renin inhibitors (DRIs) provides a new approach to block the RAS, but the effects of DRIs on renal and systemic vascular functio...

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Detalhes bibliográficos
Main Authors: Cherney, David Z.I., Lai, Vesta, Scholey, James W., Miller, Judith A., Zinman, Bernard, Reich, Heather N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2010
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809283/
https://ncbi.nlm.nih.gov/pubmed/19889802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc09-1303
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