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Hypoxia/Reoxygenation Impairs Memory Formation via Adenosine-Dependent Activation of Caspase 1

After hypoxia, a critical adverse outcome is the inability to create new memories. How anterograde amnesia develops or resolves remains elusive, but a link to brain-based IL-1 is suggested due to the vital role of IL-1 in both learning and brain injury. We examined memory formation in mice exposed t...

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Main Authors: Chiu, Gabriel S., Chatterjee, Diptaman, Darmody, Patrick T., Walsh, John P., Meling, Daryl D., Johnson, Rodney W., Freund, Gregory G.
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476834/
https://ncbi.nlm.nih.gov/pubmed/23035103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0704-12.2012
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