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CNVs leading to fusion transcripts in individuals with autism spectrum disorder

There is strong evidence that rare copy number variants (CNVs) have a role in susceptibility to autism spectrum disorders (ASDs). Much research has focused on how CNVs mediate a phenotypic effect by altering gene expression levels. We investigated an alternative mechanism whereby CNVs combine the 5′...

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Main Authors: Holt, Richard, Sykes, Nuala H, Conceição, Inês C, Cazier, Jean-Baptiste, Anney, Richard JL, Oliveira, Guiomar, Gallagher, Louise, Vicente, Astrid, Monaco, Anthony P, Pagnamenta, Alistair T
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476715/
https://ncbi.nlm.nih.gov/pubmed/22549408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2012.73
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