Metabotropic actions of the volatile anaesthetic sevoflurane increase protein kinase Mζ synthesis and induce immediate preconditioning protection of rat hippocampal slices

Anaesthetic preconditioning occurs when a volatile anaesthetic, such as sevoflurane, is administered before a hypoxic or ischaemic insult; this has been shown to improve neuronal recovery after the insult. We found that sevoflurane-induced preconditioning in the rat hippocampal slice enhances the hy...

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Detalhes bibliográficos
Main Authors: Wang, Jun, Meng, Fanli, Cottrell, James E, Sacktor, Todd C, Kass, Ira S
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2012
Assuntos:
Neuroscience: Neurobiology of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476650/
https://ncbi.nlm.nih.gov/pubmed/22674720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.233965
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