Deficiency of sphingomyelin synthase-1 but not sphingomyelin synthase-2 causes hearing impairments in mice

Sphingomyelin (SM) is a sphingolipid reported to function as a structural component of plasma membranes and to participate in signal transduction. The role of SM metabolism in the process of hearing remains controversial. Here, we examined the role of SM synthase (SMS), which is subcategorized into...

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Detalhes bibliográficos
Main Authors: Lu, Mei-Hong, Takemoto, Makoto, Watanabe, Ken, Luo, Huan, Nishimura, Masataka, Yano, Masato, Tomimoto, Hidekazu, Okazaki, Toshiro, Oike, Yuichi, Song, Wen-Jie
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2012
Assuntos:
Neuroscience: Behavioural/Systems/Cognitive
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476646/
https://ncbi.nlm.nih.gov/pubmed/22641779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.235846
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