Deficiency of sphingomyelin synthase-1 but not sphingomyelin synthase-2 causes hearing impairments in mice

Sphingomyelin (SM) is a sphingolipid reported to function as a structural component of plasma membranes and to participate in signal transduction. The role of SM metabolism in the process of hearing remains controversial. Here, we examined the role of SM synthase (SMS), which is subcategorized into...

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Bibliografiske detaljer
Main Authors: Lu, Mei-Hong, Takemoto, Makoto, Watanabe, Ken, Luo, Huan, Nishimura, Masataka, Yano, Masato, Tomimoto, Hidekazu, Okazaki, Toshiro, Oike, Yuichi, Song, Wen-Jie
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2012
Fag:
Neuroscience: Behavioural/Systems/Cognitive
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476646/
https://ncbi.nlm.nih.gov/pubmed/22641779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.235846
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