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Discovery of small molecule cancer drugs: Successes, challenges and opportunities

The discovery and development of small molecule cancer drugs has been revolutionised over the last decade. Most notably, we have moved from a one‐size‐fits‐all approach that emphasized cytotoxic chemotherapy to a personalised medicine strategy that focuses on the discovery and development of molecul...

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Autors principals: Hoelder, Swen, Clarke, Paul A., Workman, Paul
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476506/
https://ncbi.nlm.nih.gov/pubmed/22440008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2012.02.004
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