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Bayesian Inference of Signaling Network Topology in a Cancer Cell Line

Motivation: Protein signaling networks play a key role in cellular function, and their dysregulation is central to many diseases, including cancer. To shed light on signaling network topology in specific contexts, such as cancer, requires interrogation of multiple proteins through time and statistic...

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Détails bibliographiques
Auteurs principaux: Hill, Steven M., Lu, Yiling, Molina, Jennifer, Heiser, Laura M., Spellman, Paul T., Speed, Terence P., Gray, Joe W., Mills, Gordon B., Mukherjee, Sach
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476330/
https://ncbi.nlm.nih.gov/pubmed/22923301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts514
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