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Bayesian Inference of Signaling Network Topology in a Cancer Cell Line

Motivation: Protein signaling networks play a key role in cellular function, and their dysregulation is central to many diseases, including cancer. To shed light on signaling network topology in specific contexts, such as cancer, requires interrogation of multiple proteins through time and statistic...

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Detalhes bibliográficos
Main Authors: Hill, Steven M., Lu, Yiling, Molina, Jennifer, Heiser, Laura M., Spellman, Paul T., Speed, Terence P., Gray, Joe W., Mills, Gordon B., Mukherjee, Sach
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476330/
https://ncbi.nlm.nih.gov/pubmed/22923301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts514
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