Dephosphorylation of HuR Protein during Alphavirus Infection Is Associated with HuR Relocalization to the Cytoplasm

We have demonstrated previously that the cellular HuR protein binds U-rich elements in the 3′ untranslated region (UTR) of Sindbis virus RNA and relocalizes from the nucleus to the cytoplasm upon Sindbis virus infection in 293T cells. In this study, we show that two alphaviruses, Ross River virus an...

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Bibliografiske detaljer
Main Authors: Dickson, Alexa M., Anderson, John R., Barnhart, Michael D., Sokoloski, Kevin J., Oko, Lauren, Opyrchal, Mateusz, Galanis, Evanthia, Wilusz, Carol J., Morrison, Thomas E., Wilusz, Jeffrey
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476290/
https://ncbi.nlm.nih.gov/pubmed/22915590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.371203
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