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Molecular Events Initiating Exit of a Copper-transporting ATPase ATP7B from the Trans-Golgi Network

The copper-transporting ATPase ATP7B has a dual intracellular localization: the trans-Golgi network (TGN) and cytosolic vesicles. Changes in copper levels, kinase-mediated phosphorylation, and mutations associated with Wilson disease alter the steady-state distribution of ATP7B between these compart...

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Bibliographic Details
Main Authors: Hasan, Nesrin M., Gupta, Arnab, Polishchuk, Elena, Yu, Corey H., Polishchuk, Roman, Dmitriev, Oleg Y., Lutsenko, Svetlana
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476272/
https://ncbi.nlm.nih.gov/pubmed/22898812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.370403
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