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Releasable Layer-by-Layer Assembly of Stabilized Lipid Nanocapsules on Microneedles for Enhanced Transcutaneous Vaccine Delivery

Here we introduce a new approach for transcutaneous drug delivery, using microneedles coated with stabilized lipid nanocapsules for delivery of a model vaccine formulation. Poly(lactide-co-glycolide) (PLGA) microneedle arrays were coated with multilayer films via layer-by-layer (LbL) assembly of a b...

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Hlavní autoři: DeMuth, Peter C., Moon, James J., Suh, Heikyung, Hammond, Paula T., Irvine, Darrell J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475723/
https://ncbi.nlm.nih.gov/pubmed/22920601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn302639r
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