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Leishmania donovani Argininosuccinate Synthase Is an Active Enzyme Associated with Parasite Pathogenesis

BACKGROUND: Gene expression analysis in Leishmania donovani (Ld) identified an orthologue of the urea cycle enzyme, argininosuccinate synthase (LdASS), that was more abundantly expressed in amastigotes than in promastigotes. In order to characterize in detail this newly identified protein in Leishma...

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Главные авторы: Lakhal-Naouar, Ines, Jardim, Armando, Strasser, Rona, Luo, Shen, Kozakai, Yukiko, Nakhasi, Hira L., Duncan, Robert C.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475689/
https://ncbi.nlm.nih.gov/pubmed/23094117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001849
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