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Leishmania donovani Argininosuccinate Synthase Is an Active Enzyme Associated with Parasite Pathogenesis

BACKGROUND: Gene expression analysis in Leishmania donovani (Ld) identified an orthologue of the urea cycle enzyme, argininosuccinate synthase (LdASS), that was more abundantly expressed in amastigotes than in promastigotes. In order to characterize in detail this newly identified protein in Leishma...

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Detalhes bibliográficos
Main Authors: Lakhal-Naouar, Ines, Jardim, Armando, Strasser, Rona, Luo, Shen, Kozakai, Yukiko, Nakhasi, Hira L., Duncan, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475689/
https://ncbi.nlm.nih.gov/pubmed/23094117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001849
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