First Discovery of Two Polyketide Synthase Genes for Mitorubrinic Acid and Mitorubrinol Yellow Pigment Biosynthesis and Implications in Virulence of Penicillium marneffei

BACKGROUND: The genome of P. marneffei, the most important thermal dimorphic fungus causing respiratory, skin and systemic mycosis in China and Southeast Asia, possesses 23 polyketide synthase (PKS) genes and 2 polyketide synthase nonribosomal peptide synthase hybrid (PKS-NRPS) genes, which is of hi...

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Bibliografiske detaljer
Main Authors: Woo, Patrick C. Y., Lam, Ching-Wan, Tam, Emily W. T., Leung, Chris K. F., Wong, Samson S. Y., Lau, Susanna K. P., Yuen, Kwok-Yung
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475676/
https://ncbi.nlm.nih.gov/pubmed/23094121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001871
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