In Situ Conversion of Melanoma Lesions into Autologous Vaccine by Intratumoral Injections of α-gal Glycolipids

Autologous melanoma associated antigens (MAA) on murine melanoma cells can elicit a protective anti-tumor immune response following a variety of vaccine strategies. Most require effective uptake by antigen presenting cells (APC). APC transport and process internalized MAA for activation of anti-tumo...

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Main Authors: Galili, Uri, Albertini, Mark R., Sondel, Paul M., Wigglesworth, Kim, Sullivan, Mary, Whalen, Giles F.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2010
Teme:
Review
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475649/
https://ncbi.nlm.nih.gov/pubmed/23087817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers2020773
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