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Aging Mechanism of Soman Inhibited Acetylcholinesterase

Acetylcholinesterase (AChE) is a crucial enzyme in the cholinergic nervous system that hydrolyses neurotransmitter acetylcholine (ACh) and terminates synaptic signals. The catalytic serine of AChE can be phosphonylated by soman, one of the most potent nerve agents, and subsequently undergo an aging...

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Autori principali: Sirin, Gulseher Sarah, Zhou, Yanzi, Lior-Hoffmann, Lee, Wang, Shenglong, Zhang, Yingkai
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475498/
https://ncbi.nlm.nih.gov/pubmed/22984913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp307790v
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