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The Antiangiogenic Compound Aeroplysinin-1 Induces Apoptosis in Endothelial Cells by Activating the Mitochondrial Pathway

Aeroplysinin-1 is a brominated metabolite extracted from the marine sponge Aplysina aerophoba that has been previously characterized by our group as a potent antiangiogenic compound in vitro and in vivo. In this work, we provide evidence of a selective induction of apoptosis by aeroplysinin-1 in end...

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Detalhes bibliográficos
Main Authors: Martínez-Poveda, Beatriz, Rodríguez-Nieto, Salvador, García-Caballero, Melissa, Medina, Miguel-Ángel, Quesada, Ana R.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475271/
https://ncbi.nlm.nih.gov/pubmed/23118719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md10092033
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