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The anti-angiogenic 8-epipuupehedione behaves as a potential anti-leukaemic compound against HL-60 cells

We have previously reported that 8-epipuupehedione, a synthetic derivative of sesquiterpenes found in several kinds of sponges, is a potent inhibitor of angiogenesis. Here, we show that 8-epipuupehedione is also a potent anti- leukaemic compound, targeting three hallmarks of malignancy: proliferatio...

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Detalhes bibliográficos
Main Authors: Martínez-Poveda, Beatriz, Quesada, Ana R, Medina, Miguel Ángel
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822555/
https://ncbi.nlm.nih.gov/pubmed/18419606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2007.00134.x
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