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The Drosophila cytokine Unpaired 2 regulates physiological homeostasis by remotely controlling Insulin secretion

In Drosophila the fat body (FB), a functional analog of the vertebrate adipose tissue, is the 'nutrient sensor' that conveys the nutrient status to the insulin producing cells (IPCs) in the fly brain to release insulin-like peptides (Dilps). Dilp secretion in turn regulates energy balance...

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Detalhes bibliográficos
Main Authors: Rajan, Akhila, Perrimon, Norbert
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475207/
https://ncbi.nlm.nih.gov/pubmed/23021220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.08.019
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