TPC Proteins Are Phosphoinositide-activated Sodium-selective Ion Channels in Endosomes and Lysosomes

Mammalian Two-Pore Channels (TPC1, 2; TPCN1, TPCN2) encode ion channels in intracellular endosomes and lysosomes and were proposed to mediate endolysosomal calcium release triggered by the second messenger, nicotinic acid adenine dinucleotide phosphate (NAADP). By directly recording TPCs in endolyso...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wang, Xiang, Zhang, Xiaoli, Dong, Xian-ping, Samie, Mohammad, Li, Xinran, Cheng, Xiping, Goschka, Andrew, Shen, Dongbiao, Zhou, Yandong, Harlow, Janice, Zhu, Michael X., Clapham, David E., Ren, Dejian, Xu, Haoxing
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475186/
https://ncbi.nlm.nih.gov/pubmed/23063126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.08.036
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