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Medial prefrontal lesions in mice impair sustained attention but spare maintenance of information in working memory

Working memory and attention are complex cognitive functions that are disrupted in several neuropsychiatric disorders. Mouse models of such human diseases are commonly subjected to maze-based tests that can neither distinguish between these cognitive functions nor isolate specific aspects of either...

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Detalhes bibliográficos
Main Authors: Kahn, Julia B., Ward, Ryan D., Kahn, Lora W., Rudy, Nicole M., Kandel, Eric R., Balsam, Peter D., Simpson, Eleanor H.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475157/
https://ncbi.nlm.nih.gov/pubmed/23073640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.026302.112
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