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Identification Of Small Molecule TRABID Deubiquitinase Inhibitors By Computation-Based Virtual Screen
BACKGROUND: Wnt/β-catenin-mediated gene transcription plays important roles in a wide range of biological and pathophysiological processes including tumorigenesis where β-catenin-mediated transcription activity frequently elevates. TRABID, a deubiquitinase, was shown to have a positive Wnt/β-catenin...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3475094/ https://ncbi.nlm.nih.gov/pubmed/22584113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6769-12-4 |
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