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A coarse-grained α-carbon protein model with anisotropic hydrogen-bonding

We develop a sequence based α-carbon model to incorporate a mean field estimate of the orientation dependence of the polypeptide chain that gives rise to specific hydrogen bond pairing to stabilize α-helices and β-sheets. We illustrate the success of the new protein model in capturing thermodynamic...

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Sonraí Bibleagrafaíochta
Main Authors: Yap, Eng-Hui, Fawzi, Nicolas Lux, Head-Gordon, Teresa
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474853/
https://ncbi.nlm.nih.gov/pubmed/17879350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.21515
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