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Involvement of CXCR4 Chemokine Receptor in Metastastic HER2-Positive Esophageal Cancer
A functional linkage of the structurally unrelated receptors HER2 and CXCR4 has been suggested for breast cancer but has not been evaluated for esophageal carcinoma. The inhibition of HER2 leads to a reduction of primary tumor growth and metastases in an orthotopic model of esophageal carcinoma. The...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2012
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3474831/ https://ncbi.nlm.nih.gov/pubmed/23082154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047287 |
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