CD200R1 Supports HSV-1 Viral Replication and Licenses Pro-Inflammatory Signaling Functions of TLR2

The CD200R1:CD200 axis is traditionally considered to limit tissue inflammation by down-regulating pro-inflammatory signaling in myeloid cells bearing the receptor. We generated CD200R1(−/−) mice and employed them to explore both the role of CD200R1 in regulating macrophage signaling via TLR2 as wel...

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Detalhes bibliográficos
Main Authors: Soberman, Roy J., MacKay, Christopher R., Vaine, Christine A., Ryan, Glennice Bowen, Cerny, Anna M., Thompson, Mikayla R., Nikolic, Boris, Primo, Valeria, Christmas, Peter, Sheiffele, Paul, Aronov, Lisa, Knipe, David M., Kurt-Jones, Evelyn A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474780/
https://ncbi.nlm.nih.gov/pubmed/23082204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047740
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