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Role of Specific Innate Immune Responses in Herpes Simplex Virus Infection of the Central Nervous System

Herpes simplex virus 1 (HSV-1) causes a spectrum of disease, including herpes labialis, herpes keratitis, and herpes encephalitis, which can be lethal. Viral recognition by pattern recognition receptors plays a central role in cytokine production and in the generation of antiviral immunity. The rela...

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Detalhes bibliográficos
Main Authors: Wang, Jennifer P., Bowen, Glennice N., Zhou, Shenghua, Cerny, Anna, Zacharia, An, Knipe, David M., Finberg, Robert W., Kurt-Jones, Evelyn A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302371/
https://ncbi.nlm.nih.gov/pubmed/22171256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06010-11
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