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Activation of Fms-Like Tyrosine Kinase 3 Signaling Enhances Survivin Expression in a Mouse Model of Rheumatoid Arthritis

Survivin is known as an inhibitor of apoptosis and a positive regulator of cell division. We have recently identified survivin as a predictor of joint destruction in patients with rheumatoid arthritis (RA). Flt3 ligand (Flt3L) is expressed in the inflamed joints and has adjuvant properties in arthri...

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Detalhes bibliográficos
Main Authors: Andersson, Sofia E. M., Svensson, Mattias N. D., Erlandsson, Malin C., Dehlin, Mats, Andersson, Karin M. E., Bokarewa, Maria I.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474718/
https://ncbi.nlm.nih.gov/pubmed/23082191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047668
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