Clinical and Biomarker Changes in Dominantly Inherited Alzheimer’s Disease

BACKGROUND: The order and magnitude of pathologic processes in Alzheimer’s disease are not well understood, partly because the disease develops over many years. Autosomal dominant Alzheimer’s disease has a predictable age at onset and provides an opportunity to determine the sequence and magnitude o...

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Main Authors: Bateman, Randall J., Xiong, Chengjie, Benzinger, Tammie L.S., Fagan, Anne M., Goate, Alison, Fox, Nick C., Marcus, Daniel S., Cairns, Nigel J., Xie, Xianyun, Blazey, Tyler M., Holtzman, David M., Santacruz, Anna, Buckles, Virginia, Oliver, Angela, Moulder, Krista, Aisen, Paul S., Ghetti, Bernardino, Klunk, William E., McDade, Eric, Martins, Ralph N., Masters, Colin L., Mayeux, Richard, Ringman, John M., Rossor, Martin N., Schofield, Peter R., Sperling, Reisa A., Salloway, Stephen, Morris, John C.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474597/
https://ncbi.nlm.nih.gov/pubmed/22784036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1202753
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