Sustained Response and Prevention of Damage Progression in Patients With Neonatal-Onset Multisystem Inflammatory Disease Treated With Anakinra: A Cohort Study to Determine Three- and Five-Year Outcomes

OBJECTIVE: Blocking interleukin-1 with anakinra in patients with the autoinflammatory syndrome neonatal-onset multisystem inflammatory disease (NOMID) reduces systemic and organ-specific inflammation. However, the impact of long-term treatment has not been established. This study was undertaken to e...

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Detalhes bibliográficos
Main Authors: Sibley, Cailin H., Plass, Nikki, Snow, Joseph, Wiggs, Edythe A., Brewer, Carmen C., King, Kelly A., Zalewski, Christopher, Kim, H. Jeffrey, Bishop, Rachel, Hill, Suvimol, Paul, Scott M., Kicker, Patrick, Phillips, Zachary, Dolan, Joseph G., Widemann, Brigitte, Jayaprakash, Nalini, Pucino, Frank, Stone, Deborah L., Chapelle, Dawn, Snyder, Christopher, Butman, John A., Wesley, Robert, Goldbach-Mansky, Raphaela
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474541/
https://ncbi.nlm.nih.gov/pubmed/22294344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.34409
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