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A De Novo Germline APC Mutation (3927del5) in a Patient with Familial Adenomatous Polyposis: Case Report and Literature Review

INTRODUCTION: Characterized by the development of hundreds to thousands of colonic adenomas, classic familial adenomatous polyposis (FAP) is one of the most common hereditary syndromes associated with an increased risk of colorectal cancer. Several studies have attempted to correlate specific APC mu...

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Autori principali: Zeichner, Simon B., Raj, Naveen, Cusnir, Mike, Francavilla, Michael, Hirzel, Alicia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Libertas Academica 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474461/
https://ncbi.nlm.nih.gov/pubmed/23115482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/CMO.S10178
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